超,男,主治医师,讲师,博士在读。2003年毕业于南京医科大学后开始从事泌尿外科临床、教学和科研工作,熟练掌握泌尿系结石和肿瘤的微创治疗,长期致力于膀胱肿瘤的基础和临床研究,尤其是膀胱癌的个性化诊断和治疗。专业研究方向为膀胱癌的基础、临床研究及综合治疗。目前主持自然科学基金青年基金课题1项,作为重要成员参与自然科学基金课题1项,省级课题3项。获江苏省卫生厅新技术引进二等奖1项,获发明专利1项(排名第二),实用新型专利3项(排名第二)。【科研项目】1.自然科学基金青年基金:miR-141在6P22扩增膀胱移行癌中与E2F3/Rb信号通路交互调控机制的研究2. 自然科学基金:miR-218在膀胱癌侵袭性中的机制研究主要参与者3. 江苏省自然科学基金 :膀胱癌中靶向miR-21膀胱灌注的基础研究主要参与者4.江苏省“科教兴卫”工程医学核心学科子课题:雷帕霉素靶向灌注治疗高危非肌层浸润性膀胱移行细胞癌研究主要参与者【成果】1. 江苏省卫生厅新技术引进二等奖:精囊镜应用于精囊疾病的诊断和治疗【发表文章】1. Li P, Song N, Yin C, Zhang W, Li J, Hua L, Wang Z, Cheng G. Glans-Preserving Surgery for Superficial Penile Cancer. J Androl. 2012 May-Jun;33(3):435-40. Epub 2011 Aug 25.2. Xu B, Li P, Niu X, Zhang X, Wang Z, Qin C, Li J, Jia Y, Wu H, Zhang W. A New Method of Chronic and Recurrent Seminal Vesiculitis Treatment. J Endourol. 2011 ,25(11):1815-1818. (并列)3. Feng Ninghan. Xu Bin. Tao Jun. Li Pengchao et al. A miR-125b binding site polymorphism in bone morphogenetic protein membrane receptor type IB gene and prostate cancer risk in China. Mol Biol Rep. 2012 Jan;39(1):369-73. Epub 2011 May 10. (并列)4. Tao J, Wu D, Li P, Xu B, Lu Q,Zhang W. microRNA-18a, a member of the oncogenic miR‑17-92 cluster, targets Dicer and suppresses cell proliferation in bladder cancer T24 cells. Mol Med Report. 2012 Jan;5(1):167-72.5. Tao J, Lu Q, Wu D, Li P, Xu B, Qing W, Wang M, Zhang Z, Zhang W. microRNA-21 modulates cell proliferation and sensitivity to doxorubicin in bladder cancer cells. Oncol Rep. 2011 Jun;25(6):1721-9.6. Wu D, Tao J, Xu B, Qing W, Li P, Lu Q and Zhang W. Phosphatidylinositol 3-Kinase Inhibitor LY294002 Suppresses Proliferation and Sensitizes Doxorubicin Chemotherapy in Bladder Cancer Cells. Urol Int. 2011;87(1):105-13. Epub 2011 May 18.7. Deyao Wu, Jun Tao, Bin Xu, Pengchao Li, Qiang Lu, Wei Zhang. Downregulation of Dicer, a component of the microRNA machinery, in bladder cancer. Mol Med Report. 2012 Mar;5(3):695-9. doi: 10.3892/mmr.2011.711. Epub 2011 Dec 14.8. Xu B, Feng NH, Li PC, Tao J, Wu D, Zhang ZD, Tong N, Wang JF, Song NH, Zhang W et al. A functional polymorphism in Pre-miR-146a gene is associated with prostate cancer risk and mature miR-146a expression in vivo. Prostate. 2010 Apr 1;70(5):467-72.9. Xu B, Li JM, Tong N, Tao J, Li PC, Song NH, Zhang W, Wu HF, Feng NH and Hua LX. VEGFA +936C>T polymorphism and cancer risk: a meta-ysis. Cancer Genet Cytogenet. 2010 Apr 1;198(1):7-14.10. Xu B, Mi YY, Min ZC, Cheng G, Tong N, Tao J, Li PC, Wang ML, Tang JL, Zhang ZD et al. p53 codon 72 increased biochemical recurrence risk after radical prostatectomy in a southern Chinese population. Urol Int. 2010;85(4):401-5. Epub 2010 Jul 20.11. Xu B, Niu X, Zhang X, Tao J, Wu D, Wang Z, Li P, Zhang W, Wu H, Feng N et al. miR-143 decreases prostate cancer cells proliferation and migration and enhances their sensitivity to docetaxel through suppression of KRAS. Mol Cell Biochem. 2011 Apr;350(1-2):207-13.12. Xu B, Niu XB, Wang ZD, Cheng W, Tong N, Mi YY, Min ZC, Tao J, Li PC, Zhang W et al. IL-6 -174G>C polymorphism and cancer risk: a meta-ysis involving 29,377 cases and 37,739 controls. Mol Biol Rep. 2011 Apr;38(4):2589-96. Epub 2010 Nov 23.13. Xu B, Wang J, Tong N, Mi Y, Min Z, Tao J, Li P, Cheng G, Li J, Wang M et al. A functional polymorphism in MSMB gene promoter is associated with prostate cancer risk and serum MSMB expression. Prostate. 2010 Jul 1;70(10):1146-52.14. Xu B, Xu Z, Cheng G, Min ZC, Mi Y, Zhang ZZ, Tao J, Li PC, Wang ML, Tang JL et al. Association between polymorphisms of TP53 and MDM2 and prostate cancer risk in southern Chinese. Cancer Genet Cytogenet. 2010 Oct 15;202(2):76-81.15. 超, 陶俊, 吕强, 吴德尧, 秦伟杰, 张炜.MiR-143在膀胱移行细胞癌中的表达和功能. 南京医科大学学报,2010.09;30(9): 1235-123916.超, 陶俊,吕强,吴德尧,秦伟杰,张炜 MiR-200c和miR-141在膀胱移行细胞癌中的表达研究南京医科大学学报.2010,06;30(6):768-78617. 超,宋日进,孟小鑫,吕强,张炜,殷长军,李杰 P双频双导管超声碎石系统治疗肾结石分析. 临床泌尿,2012.01, 27(1): 46-48,5118. 超,秦超,王增军,张炜,李杰 , 国产三件套可膨胀型假体植入治疗勃起功能障碍. 南京医科大学学报, 2012.01, 32(1): 150-152